Age and Fertility: IVF with PGTA testing or Egg Donation?
by Eirini Neofytou, last updated 07 Dec 2024,
2 min read
For women in advanced maternal age, the journey to parenthood may present unique challenges. At Newlife IVF Greece, we understand these complexities and offer advanced fertility treatment options to help you achieve your dream. Let's explore two primary treatment options: using your eggs with PGT-A testing or pursuing egg donation.
Treatment with Own Eggs and PGT-A Testing
When using your own eggs in advanced maternal age:
- PGT-A (Preimplantation Genetic Testing for Aneuploidies) can screen embryos for chromosomal abnormalities
- This testing helps select those embryos suitable for transfer
- Success rates depend on age and egg quality
- The process requires sufficient egg production through stimulation
- Time is a crucial factor, as egg quality and quantity decrease with age
Advantages:
- Genetic connection to both parents
- Ability to screen for chromosomal issues
- Reduced risk of miscarriage with tested embryos
Challenges:
- Lower success rates in women over 40
- Fewer viable eggs and embryos
- Higher cost due to additional testing
- May require multiple cycles

Egg Donation Option
Egg donation presents an alternative path:
- Uses eggs from young, healthy donors
- Higher success rates regardless of recipient's age
- More embryos available for transfer and freezing
- Reduced genetic risks due to donor age
Advantages:
- Significantly higher success rates
- Reduced risk of chromosomal abnormalities
- Option for future siblings from the same donor
Considerations:
- Genetic connection to one parent only
- Emotional adjustment to using donor eggs
- Need to consider disclosure decisions
- Different cost structure
Comparing Success Rates
The statistics speak volumes:
- Own eggs with PGT-A (age 40+): 20-30% success rate per transfer
- Donor eggs: 50-60% success rate per transfer
Making Your Decision
Consider these factors:
- Your age and ovarian reserve
- Time constraints
- Budget considerations
- Emotional readiness for either option
- Future family planning goals
Both options offer viable paths to parenthood, but their success rates and considerations differ significantly. While PGT-A testing with one's eggs maintains a complete genetic connection, egg donation provides higher success rates. It may be more suitable for women in advanced maternal age or with diminished ovarian reserve.
Take the Next Step
Don't let age define your path to parenthood. At Newlife IVF Greece, we're not just a healthcare provider, we're your partners in this journey. We're here to help you make an informed decision based on your unique circumstances. Contact our fertility specialists today for a personalised consultation to discuss your options. Book your consultation now!

Eirini Neofytou, BSc, PhD
Eirini is an Embryologist working in the IVF laboratory and a member of the scientific team of Newlife IVF Greece.