“Do We Really Need All These Tests?” How Clinics Decide Which Fertility Investigations You Need
by Magda Sotiriadou, last updated 09 Nov 2026,
3 min read
Many couples quietly ask us the same thing at their first appointment: “Do we really need all these tests?” When you see a long list of bloods, scans and specialist exams, it can feel overwhelming, expensive and even a bit scary.

A good fertility work‑up does not start with tests; it starts with your story. At Newlife IVF Greece, your doctor first takes a detailed medical history, asks about your cycles, previous pregnancies, any miscarriages, past surgeries and how long you have been trying. Only then do we decide which basic investigations are truly necessary for you and your partner, because not every test adds useful information in every case.
There are a few core tests that almost everyone needs. For women, this usually includes hormone blood tests such as AMH, FSH and LH to understand ovarian reserve and ovulation, and a transvaginal ultrasound to look at the uterus and count antral follicles. For men, a semen analysis is essential to check sperm count, movement and shape, because male factor issues are present in a large percentage of couples, sometimes without obvious symptoms. Infectious‑disease screening (for example HIV, hepatitis B and C, syphilis) is also required by law and for your safety before any IVF or donation treatment.
Beyond this basic panel, extra tests are chosen, not automatic. If your history or first results suggest a possible problem in the uterus or fallopian tubes, your doctor may recommend imaging such as HSG, HyCoSy, sonohysterogram or hysteroscopy to check that the cavity is healthy and the tubes are open. If there have been recurrent miscarriages or very low sperm counts, more specialised investigations like genetic testing, karyotype, thrombophilia or immune tests may be considered – but only when they are likely to change the treatment plan.
Online, you may see long “must‑do” test lists on forums or TikTok, but more tests do not automatically mean better care. Many advanced investigations are expensive, not always well‑supported by evidence in every situation, and can sometimes add confusion without improving your chances. Our approach at Newlife is to start with the tests most likely to explain your specific situation and to add extra layers only when there is a clear medical reason, in line with European guidelines and up‑to‑date science.
From your side, a good question to ask is: “How will this test change what we do next?” If a test will guide the choice between IUI and IVF, change your stimulation protocol, suggest surgery (for example to remove a polyp) or highlight a risk in pregnancy, it is usually worth considering. If it is unlikely to change your plan, your doctor should explain why they still recommend it – or be open to postponing it. At Newlife, we try to be transparent about which tests are essential, which are optional and which may be relevant later if first‑line treatments do not work as expected.
If you are looking at a long list of investigations and feeling lost or worried about costs, you are welcome to contact our medical team for a free, consultation. Together we can review which tests you have already done, which ones are genuinely needed next and how to build a step‑by‑step plan that is thorough, evidence‑based and tailored to you – focusing on what will truly help, not just what is available.
Magda Sotiriadou, BSc
Magda is a Midwife and International Patient Coordinator at Newlife.